The retail corridors of Lodge Lane, Smithdown Road and Lawrence Road are being backed by councillors in the bid to gain World Host Recognition.
The area, known as Liverpool 1578, has seen the occupancy rate rise from 71% to 83% in the last four years, an increase of almost a fifth .
In a statement, the office of City Mayor Joe Anderson said: “As the area repopulates from a number of significant on-going housing development schemes, then we predict that this positive trend will only increase.”
To increase the chances of success, Liverpool City Council is offering a one-day training course in world-class customer service to businesses in Liverpool 1578.
Nick Small, Cabinet member for skills, enterprise and employment, said: “We want Liverpool 1578 to become the first in the Liverpool City Region to achieve this status.
“It is an investment in the people as well as the infrastructure and we believe that investment in people will improve sales and profits, making the area a better place for business owners and those who live and work in the area.
“This is why Liverpool City Council is backing this training.”
If successful, it is hoped the improved status will attract large numbers of visitors to the area and promote a sense of pride amongst the small businesses.
The award will also provide an alternative shopping experience away from the city centre.